Fig. 6. The mechanism of C-type natriuretic peptide (CNP), testosterone, and estradiol in promoting natriuretic peptide receptor 2 (NPR2) expression in mouse Leydig cells. (A) The expression of NPR2 after stimulation with CNP, testosterone and estradiol with or without flutamide and ICI182780 in mouse Leydig cells. (B) The expression of Cyp19a1 after stimulation with CNP, testosterone and estradiol with or without flutamide and ICI182780 in mouse Leydig cells. The Σ-actin was used as internal control. The data are presented as the mean±standard error of mean of three independent experiments. Bars with different letters are significantly different (p<0.05).
