Table 2.
Prevalence (%) of mutations in the K13 gene in clinical isolates from the China-Myanmar border.
| Year | n | NNa | K189T | E252Q | P441L | F446I | N458Y | G533S | R539T | P574L | C580Y | A676D | H719N |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2007 | 17 | 47.1 | – | – | 5.9 | 17.6 | – | – | – | 11.8 | – | – | – |
| 2008 | 19 | 47.4 | – | 10.5 | – | 21.1 | – | – | 5.3 | 5.3 | 5.3 | 5.3 | – |
| 2009 | 14 | 64.3 | – | – | – | 7.1 | – | – | – | – | – | 7.1 | 21.4 |
| 2010–2012 | 9 | 77.8 | – | – | – | 33.3 | – | – | – | – | – | – | – |
| 2013 | 40 | 90.0 | 5.0 | – | – | 62.5 | 2.5 | – | – | – | – | – | – |
| 2014–2016 | 34 | 100.0 | – | – | – | 55.9 | – | 44.1 | – | – | – | – | – |
| Total | 133 | 77.4 | 1.5 | 1.5 | 0.8 | 41.4 | 0.8 | 11.3 | 0.8 | 2.3 | 0.8 | 1.5 | 2.3 |
a
NN insertion at amino acid 136–137 of K13 gene.