Fig. 4. SIX1 was a target of miR-362, and the expression of SIX1 was mediated by miR-362. (A) TargetScan was employed to predict SIX1 as a potential target gene of miR-362. (B) Luciferase reporter assay was applied to determine whether miR-362 targets SIX1. (C) miR-362 regulated the expression of SIX1. ^#p>0.05, ^**p<0.01, ^***p<0.001.