Table 2. Electrocardiographic, Echocardiographic, and Invasive Hemodynamic Parameters and Endomyocardial Biopsy Results in Each Group.
| Sustained RBBB (n=10) | Newly developed RBBB (n=13) | Sustained non-RBBB (n=28) | ||||
|---|---|---|---|---|---|---|
| 1 month | 1 year | 1 month | 1 year | 1 month | 1 year | |
| Electrocardiogram | ||||||
| QRS width (ms) | 109.6±11.1* | 112.6±8.8 | 87.0±10.4 | 110.6±12.1 | 82.0±8.7 | 90.1±10.1∥ |
| PR interval (ms) | 133.4±13.0 | 148.6±25.7 | 143.8±14.6 | 164.8±13.7§ | 145.4±16.5 | 149.2±18.3 |
| QTc (ms) | 456.8±27.0 | 466.5±22.2 | 446.0±25.8 | 441.9±23.0 | 446.0±25.8 | 441.9±23.0 |
| Right heart catheterization | ||||||
| RVSP (mm Hg) | 30.2±7.9 | 28.3±7.4 | 31.1±6.6 | 26.3±6.8 | 30.3±6.6 | 28.4±7.8 |
| RVDP (mm Hg) | 4.5±7.2 | 1.3±4.0 | 2.6±2.4 | 0.1±3.5 | 3.2±3.3 | 1.6±2.7 |
| RVMP (mm Hg) | 16.0±7.2 | 12.4±2.7 | 14.8±4.7 | 11.0±5.1 | 15.0±3.8 | 14.4±5.1 |
| PASP (mm Hg) | 27.6±8.5 | 26.5±5.7 | 29.1±6.2 | 24.8±7.5 | 29.0±7.7 | 27.4±6.5 |
| PADP (mm Hg) | 10.7±2.9 | 11.3±2.8 | 13.4±4.3 | 9.9±4.4 | 12.3±4.6 | 12.8±4.7 |
| PAMP (mm Hg) | 18.3±3.2 | 18.2±3.9 | 18.0±5.7 | 17.0±5.7 | 19.7±5.8 | 19.7±5.4 |
| PCWP (mm Hg) | 8.7±4.3 | 9.6±2.8 | 12.8±4.5 | 9.2±3.8 | 10.7±3.3 | 12.1±6.1 |
| Echocardiographic data | ||||||
| LVEF (%) | 68.2±6.3 | 65.2±6.8 | 66.0±7.2 | 68.2±4.3 | 67.5±5.5 | 65.0±7.9 |
| LVMI (g/m2) | 94.1±21.5 | 84.5±13.1 | 106.9±36.7 | 93.9±28.6 | 94.2±24.9 | 81.7±17.3 |
| LAVI (mL/m2) | 38.6±12.8 | 36.0±11.0 | 63.2±24.1† | 60.6±25.9‡ | 39.2±13.9 | 38.4±18.1 |
| E velocity (m/s) | 0.71±0.12 | 0.70±0.21 | 0.83±0.27 | 0.79±0.23 | 0.73±0.21 | 0.75±0.17 |
| E′ velocity (cm/s) | 6.3±2.4 | 8.0±2.8 | 5.7±2.2 | 7.1±2.7 | 6.2±1.8 | 7.7±2.0 |
| E/E′ | 12.4±3.7 | 9.3±3.1 | 15.2±5.8 | 11.8±4.1 | 12.7±4.5 | 10.2±2.8 |
| RVSP (mm Hg) | 33.8±9.1 | 29.2±8.4 | 35.1±11.6 | 26.0±8.7 | 34.6±9.3 | 29.5±5.1 |
| TAPSE (mm) | 14.0±3.9 | 16.8±0.6 | 15.6±3.4 | 16.0±2.6 | 15.7±2.9 | 15.9±2.2 |
| TV TDI S' (cm/s) | 9.1±1.8 | 10.2±2.0 | 8.6±3.2 | 10.0±2.2 | 8.6±2.4 | 9.3±2.6 |
| Histology | ||||||
| Graft rejection (≥1) | 7 (70.0) | 1 (10.0) | 6 (46.2) | 9 (69.2) | 14 (50.0) | 13 (46.4) |
| Immunosuppressant level | ||||||
| Tacrolimus level (ng/mL) | 10.9±5.8 | 9.5±3.8 | 8.9±2.1 | 7.9±2.2 | 9.5±3.5 | 9.8±3.1 |
LAVI, left atrial volume index; LVMI, left ventricular mass index; PCWP, pulmonary capillary wedge pressure; RBBB, right bundle branch block; RVSP, right ventricular systolic pressure; RVDP, right ventricular diastolic pressure; RVMP, right ventricular mean pressure; PASP, pulmonary artery systolic pressure; PADP, pulmonary artery diastolic pressure; PAMP, pulmonary artery mean pressure; PCWP, pulmonary capillary wedge pressure; TAPSE, tricuspid annular plane systolic excursion; TV TDI S', tricuspid valve tissue Doppler imaging S'.
Values are expressed as mean±SD or number (percentage).
p<0.05, by ANOVA with post hoc test using Bonferroni technique (*sustained RBBB group vs. newly developed RBBB group and sustained non-RBBB group at 1 month following heart transplantation; †newly developed RBBB group vs. sustained RBBB group and sustained non-RBBB group at 1 month following heart transplantation; ‡newly developed RBBB group vs. sustained RBBB group and sustained non-RBBB group at 1 year following heart transplantation; §newly developed RBBB group vs. sustained non-RBBB group at 1 year following heart transplantation; ∥sustained non-RBBB group vs. sustained RBBB group and newly developed RBBB group at 1 year following heart transplantation).