Table 2.
In vivo antinociceptive activity by the tail immersion method.
| Group | Dosage | Basal Reaction time (min) |
Reaction time (min) |
||
|---|---|---|---|---|---|
| 30 | 60 | 120 | |||
| Control | 2 ml/kg | 2.34 ± 0.14 | 2.44 ± 0.15 | 2.48 ± 0.16 | 2.52 ± 0.14 |
| Indomethacin | 0.05 mol/Kg | 2.42 ± 0.06 | 3.56 ± 0.09∗∗∗ | 3.60 ± 0.07∗∗∗ | 3.66 ± 0.05∗∗∗ |
| 1f | 0.05 mol/Kg | 2.64 ± 0.05 | 2.42 ± 0.03 | 2.52 ± 0.03 | 2.58 ± 0.03 |
| 1g | 0.05 mol/Kg | 2.78 ± 0.05 | 2.96 ± 0.05∗∗ | 3.00 ± 0.03∗∗ | 3.04 ± 0.05∗∗ |
| 1h | 0.05 mol/Kg | 2.28 ± 0.08 | 2.90 ± 0.07∗ | 2.92 ± 0.04∗ | 2.94 ± 0.06∗ |
| 1i | 0.05 mol/Kg | 2.60 ± 0.07 | 2.98 ± 0.08∗∗ | 3.02 ± 0.05∗∗ | 2.96 ± 0.07∗∗ |
| 1j | 0.05 mol/Kg | 2.44 ± 0.05 | 2.58 ± 0.06 | 2.64 ± 0.09 | 2.70 ± 0.08 |
Data is analyzed by one way ANOVA followed by Dunnett's ‘t’ test and expressed as mean ± SEM from six observations; ***p < 0.001, ** indicates P < 0.01 & * indicates P < 0.05.