Table 2.

B cell and plasma cell infiltrates by length of graft survival.

Graft Survival Group	Patient	Graft Survival (years)	B Cells			Plasma Cells			Donor Specific Antibody	C4d
			Nodules	Diffuse	Neointima	B Cell Nodule	Diffuse	Neointima
Short (<3 years)	2	1.4	0	0	0	0	1+	2+	NS	−
	13	1.8	1–3	0	0	1+	2+	0	No DSA	+
	15	2.2	1–3	0	0	1+	0	0	NS	−
	9	2.7	1–3	1+	0	0	0	0	No DSA	NM
Intermediate (3–12 years)	10	3.6	1–3	1+	1+	1+	1+	1+	No DSA*	−
	6	5.2	>3	1+	1+	2+	2+	1+	No DSA*	−
	1	5.6	1–3	0	0	3+	3+	0	NS	+
	3	6	0	0	0	0	1+	1+	No DSA	−
	12	6.7	>3	1+	1+	1+	2+	1+	No DSA	−
	7	8.1	1–3	1+	0	1+	2+	0	NS	+
	5	10.8	1–3	1+	1+	2+	1+	1+	No DSA	−
	14	11.1	1–3	0	0	1+	0	0	No DSA	−
Long (>12 years)	11	12.3	1–3	1+	1+	2+	1+	1+	NS	−
	4	12.7	1–3	1+	2+	1+	1+	0	No DSA	−
	8	13.4	0	1+	0	0	2+	0	No DSA	NM
	16	14.6	1–3	1+	1+	2+	1+	0	No DSA	−

NS = No serum available

NM = No myocardium available for analysis

DSA = Donor Specific Antibody

^*= Low levels of non-donor MHC Class II antibodies present

⁺= positive diffuse capillary C4d staining