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White matter regions with significant higher white matter fluid signal (WFS) in cognitively impaired subjects. A shows the increased WFS in sagittal stratum. Sagittal stratum area is illustrated in B. Scatter plots C and D are related to the anterior thalamic area. Last column (E) shows the WFS of both groups as a function of age. Posterior internal capsule included as an example with no statistical difference to appreciate the extent of change in the affected white matter regions.
