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. 2019 Apr 2;20(7):1640. doi: 10.3390/ijms20071640

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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PRLR/TGFβRI/TGFβRII gene signature and its association with tumor grade and patient outcome. (A) Boxplot of PRLR/TGFβRI/TGFβRII gene signature in 1881 breast cancer cases from the GOBO database stratified according to histological grade. The band inside the box represents the median. The top and bottom of the box indicate the distance between quartile 1 (Q1), quartile 3 (Q3) and 1.5 times the interquartile range. In addition, the circles (when present) indicate the outliers. (B) PRLR/TGFβRI/TGFβRII gene signature and its association with patient outcome using distant metastasis-free survival (DMFS) as an end point in different tumor grades using 1881 breast cancer cases from the GOBO database.