NGS	Next-generation sequencing
SNV	Single nucleotide variant
SAV	Single amino acid variant
PPI	Protein-protein interaction
HBB	Hemoglobin subunit beta
HBZ	Hemoglobin subunit zeta
HBA	Hemoglobin subunit alpha
HP	Haptoglobin
PDB	Protein Data Bank
MSA	Multiple Sequence Alignment
ASA	Accessible Surface Area
NIP	Normalized Interface Propensity
HADHA	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit α