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. 2019 Mar 30;24(7):1247. doi: 10.3390/molecules24071247

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Protective effects of dioscin on H₂O₂-induced injury in PC12 cells. (A) The chemical structure of dioscin. (B) Cytotoxicity of dioscin on PC12 cells detected by MTT assay. (C) Effects of H₂O₂ on cell viability. (D) Effects of dioscin alleviated on H₂O₂-induced cell injury. (E) Effects of dioscin on LDH release in H₂O₂-injured PC12 cells. (F) Effects of dioscin on the morphological changes of PC12 cells after H₂O₂ treatment (400× magnification; Scale bar = 50 μm). Data are presented as the mean ±SD (n ≥ 5). * p < 0.05 and ** p < 0.01 compared with model group.