. 2019 Apr 9;20(7):1753. doi: 10.3390/ijms20071753

Table 2.

Anti-inflammatory activity of G. procumbens stem dry extracts in non-cellular models.

Analyte	HYAL		LOX		COX-2
Analyte	IC₅₀ (µg/mL) ^a	IC₅₀ (μg GAE/mL; µM) ^b	IC₅₀ (mg/mL) ^a	IC₅₀ (mg GAE/mL; mM) ^b	IC₅₀ (mg/mL) ^a	IC₅₀ (mg GAE/mL; mM) ^b
AE	11.67 ± 1.16 ^{A, B}	4.06	0.29 ± 0.01 ^D	0.10	0.38 ± 0.01 ^C	0.13
ME	10.26 ± 0.86 ^A	3.09	0.32 ± 0.01 ^E	0.10	0.47 ± 0.01 ^E	0.14
BE	15.09 ± 1.31 ^C	4.97	0.38 ± 0.02 ^F	0.12	0.44 ± 0.01 ^D	0.14
WE	19.11 ± 1.28 ^D	4.59	0.37 ± 0.01 ^F	0.09	0.82 ± 0.03 ^G	0.20
PB2	21.65 ± 1.03 ^E	37.42 ± 1.78 ^A	0.17 ± 0.01 ^C	0.29 ± 0.03 ^{A, B}	0.83 ± 0.04 ^G	1.43 ± 0.06 ^D
GT	28.58 ± 1.28 ^F	64.02 ± 2.87 ^B	0.56 ± 0.02 ^G	1.26 ± 0.04 ^C	0.35 ± 0.02 ^B	0.78 ± 0.03 ^B
IND	12.77 ± 1.91 ^B	35.69 ± 5.34 ^A	0.09 ± 0.01 ^A	0.26 ± 0.01 ^A	0.18 ± 0.01 ^A	0.50 ± 0.02 ^A
DEX	14.18 ± 1.05 ^C	36.13 ± 2.68 ^A	0.12 ± 0.01 ^B	0.30 ± 0.02 ^B	0.51 ± 0.02 ^F	1.29 ± 0.04 ^C
QU	30.78 ± 1.84 ^F	101.84 ± 6.09 ^C	0.09 ± 0.01 ^A	0.30 ± 0.02 ^B	0.47 ± 0.02 ^E	1.56 ± 0.05 ^E

^a,b Inhibition concentration (amount of analyte needed for 50% inhibition of enzyme activity) expressed as follows: ^a in μg/mg of the dry extract or standard/mL of the enzyme solution; ^b in μg/mg of phenolics/mL of the enzyme solution (values obtained by converting the original IC₅₀ values using the TPC levels), or µM/mM of the standard. Results are presented as mean values ± SD (n = 3). For each parameter, different capital letters given in parentheses (A–G) indicate significant differences (p < 0.05).