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Quantification (IC50) of membrane toxicity and ATP depletion by the investigated synthetic cathinones and MDMA. Unit for IC50 is mM.
| MDMA | 3-MMC | Mephedrone | Methylone | α-PVP | MDPV | Naphyrone | |
|---|---|---|---|---|---|---|---|
| Membrane toxicity | 0.74 | >2 | >2 | 1.10 | 1.04 | >2 | 0.047 |
| ATP depletion | 0.88 | 1.08 | 0.53 | 1.16 | 0.94 | 1.01 | 0.021 |
