NASH |
nonalcoholic steatohepatitis |
NAFLD |
nonalcoholic fatty liver disease |
LDLr−/−
|
low density lipoprotein receptor knockout mice |
TSG |
2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside |
SREBP |
sterol regulatory element binding protein |
FAS |
fatty acid synthase |
ACCα |
Acetyl-CoA Carboxylase α |
PPARα |
peroxisome proliferator-activated receptor α |
CPT1α |
camitine palmitoyltransferase 1α |
ACO |
Acyl Coenzyme A Oxidase |
ABCB4/B11/G5/G8 |
ATP-binding cassette transporter B4/B11/G5/G8 |
SR-BI |
scavenger receptor class B type I |
NOX2/4 |
NADPH oxidase subunit 2/4 |
CYP2E1 |
cytochrome p450 2E1 |
CYP7A1 |
cholesterol 7alpha-hydroxylase |
TC |
total cholesterol |
TG |
triglyceride |
LDL-c |
low density lipoprotein cholesterol |
HDL-c |
high density lipoprotein cholesterol |
AST |
aspartate aminotransferase |
ALT |
alanine aminotransferase |
SOD |
superoxide dismutase |
GSH |
glutathione |
CAT |
catalase |
MDA |
malondialdehyde |
DHE |
Dihydroethidium |
H&E |
hematoxylin and eosin |
TNF-α |
tumor necrosis factor-α |
IL-6 |
interleukin-6 |