Table 2.

Combined treatment of infected hFIB with compound 2 and benznidazole.

	EC50 ± SD (µM)
Compounds	Alone	Combination	CI ± SD (µM)
2	12.15 ± 6.46	2.69 ± 1.13	1.35 ± 0.04
Benznidazole	2.17 ± 0.09	2.45 ± 0.34

Cutoff: CI value of 0.30 to 0.70, synergism; 0.70 to 0.85, moderate synergism; 0.85 to 0.90, slight synergism; 0.90 to 1.10, additivity; >1.10, antagonism. CI, combination index; SD, standard deviation.