Fig. 3.

Case, female, 16 years old, pathological diagnosis of Ewing's sarcoma of the right femur, underwent P-F-B reconstruction.

A: Preoperative X-ray and MRI, showing a huge tumor with a length of 15.13 cm.

B: Tumor resection, the 3D-printed prosthesis perfectly matched the anatomical characteristics of the bone defect.

C: Installation and fixation of the bioactive prosthesis composite.

D: X-ray: one month after operation.

E: X-ray: 12 months after operation, the prosthesis was in situ without loosening. The arrow showed osseous coverage between prosthesis and residual bone.

F: X-ray: 24 months after operation, a solid integration was formed between bone and prosthesis. The arrow indicated a ‘spot welding’, which connecting edge of the prosthesis to bone.