Table 1.
#PDB Entries | #SRVs | # SRVs Buried (b) | # SRVs Exposed (c) |
---|---|---|---|
386 (D+D/N) (a) | 6621 | 3998 | 2623 |
241 (D/N) (a) | 5450 | 3325 | 2125 |
145 (D) (a) | 1171 | 673 | 498 |
(a) D = protein chains with only disease related variations, D/N = protein chains with both Disease related and Neutral variations; (b) Occurring at positions having relative solvent accessibility, RSA < 20%; (c) Occurring at position having RSA ≥ 20%. SRVs: Single Residue Variations.