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. 2019 Mar 27;20(7):1530. doi: 10.3390/ijms20071530

Table 3.

Enzymes in HVAR3D.

EC(a) #Protein Chains #D-SRVs (b) #N-SRVs (c) #D-SRVs on: #N-SRVs on:
ACTIVE SITE BINDING SITE ACTIVE SITE BINDING SITE
Oxidoreductases 64 1045 107 2 20 0 0
Transferases 71 1058 122 5 20 0 0
Hydrolases 69 1342 143 7 10 0 1
Lyases 19 260 36 0 3 0 0
Isomerases 7 236 14 0 7 0 0
Ligases 11 138 15 0 7 0 2
Multiple ECs 7 179 18 0 0 0 0
Total 248 4258 455 14 67 0 3

(a) EC = enzyme commission; (b) D-SRVs = disease-related SRVs; (c) N-SRV = neutral SRVs. Residue annotation (Active site, Binding site) is taken from the corresponding protein file in UniprotKB.