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. 2019 Mar 29;16(7):1136. doi: 10.3390/ijerph16071136

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Representative photomicrographs (200×) of KIM-1 in situ expression in the kidney of mice injected with F (0, 2, 5, 7.5 and 10 mg/kg) or U (0, 2, 4 and 5 mg/kg). The dollar symbol ($) indicates the expression of KIM-1 in the lumen of proximal tubules. The sharp symbol (#) indicates KIM-1 expression in tubular cells. The asterisk indicates KIM-1 expression in the apical pole of tubular cells. (B) The results of the semi-quantification of KIM-1 in situ expression are presented as the mean ± standard error of the mean. The asterisk represents a significant difference between the treated (n = 6) and control (n = 5) groups (general estimating equation, * p < 0.05, ** p < 0.005, *** p < 0.001).