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. 2019 Apr 3;20(7):1671. doi: 10.3390/ijms20071671

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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In vitro wound healing effect of conditioned media of LDSCs and ADSCs; effect of LDSC-CM, ADSC-CM, positive (PC) and negative (NC) control on fibroblasts’ migration (a) and wound closure (b); mean ± standard deviation (SD); sample size: n(LDSCs) = 4 and n(ADSCs) = 4 (n − number of patients per group); for each patient sample-derived CM, as well as controls, four replicates were analyzed; microscopic appearance of the “wound” 3 days after cultivation in LDSC-CM (c), ADSC-CM (d), positive control (e) and negative control (f); phase contrast with objective magnification 5×; (***) p < 0.001 compared to LDSC-CM, ADSC-CM and PC, no significant difference observed between both CM types and PC.