Table 1.
Plackett–Burman design conditions and results.
| Run | Process Parameters | Process Indices | |||||||
|---|---|---|---|---|---|---|---|---|---|
| X1 (°C) | X 2 | X 3 | X4 (h) | X5 (mL/g) | X6 (mL) | X7 (mL) | Y1 (mg/g Medicinal Slices) | Y2 (%) | |
| 1 | 50 | 4.2 | 5.0 | 2.0 | 8.0 | 60 | 100 | 0.516 | 37.7 |
| 2 | 50 | 2.4 | 4.0 | 2.0 | 10.0 | 80 | 100 | 2.72 | 53.9 |
| 3 | 100 | 2.4 | 5.0 | 4.0 | 10.0 | 60 | 50 | 9.23 | 38.7 |
| 4 | 75 | 3.3 | 4.5 | 3.0 | 9.0 | 70 | 75 | 5.17 | 65.2 |
| 5 | 50 | 2.4 | 4.0 | 2.0 | 8.0 | 60 | 50 | 2.69 | 57.2 |
| 6 | 50 | 4.2 | 5.0 | 4.0 | 8.0 | 80 | 50 | 0.970 | 58.1 |
| 7 | 100 | 2.4 | 5.0 | 2.0 | 8.0 | 80 | 50 | 10.2 | 49.0 |
| 8 | 100 | 2.4 | 4.0 | 4.0 | 8.0 | 60 | 100 | 5.09 | 45.9 |
| 9 | 75 | 3.3 | 4.5 | 3.0 | 9.0 | 70 | 75 | 5.33 | 63.8 |
| 10 | 100 | 4.2 | 5.0 | 2.0 | 10.0 | 60 | 100 | 0.881 | 33.1 |
| 11 | 50 | 2.4 | 5.0 | 4.0 | 10.0 | 80 | 100 | 10.8 | 64.2 |
| 12 | 75 | 3.3 | 4.5 | 3.0 | 9.0 | 70 | 75 | 5.61 | 62.9 |
| 13 | 100 | 4.2 | 4.0 | 2.0 | 10.0 | 80 | 50 | 0.300 | 38.8 |
| 14 | 100 | 4.2 | 4.0 | 4.0 | 8.0 | 80 | 100 | 0.238 | 28.5 |
| 15 | 50 | 4.2 | 4.0 | 4.0 | 10.0 | 60 | 50 | 0.205 | 39.5 |
X1: extraction temperature; X2: extraction pH; X3: back-extraction pH; X4: extraction time; X5: water consumption for extraction; X6: 1-butanol amount; X7: water consumption for washing; Y1: SAB yield in crude SAB solution; Y2: SAB purity in crude SAB solution.