Table 1.
The top 10 deregulated genes in CCS versus CTR.
| Gene Symbol | Name | Gene Expression ‡ | Log2FC | Adjusted p Value |
|---|---|---|---|---|
| upregulated | ||||
| SLC45A4 | Solute carrier family 45 member 4 | 1.07 | 0.57 | **** |
| NAB2 | Nuclear polyadenylated RNA-binding protein | 40.76 | 0.55 | **** |
| MPO | Myeloperoxidase | 0.49 | 0.49 | **** |
| RFLNB | Refilin-B | 18.00 | 0.46 | **** |
| SPRY2 | Protein sprouty homolog 2 | 19.00 | 0.43 | **** |
| OASL | 2′-5′-oligoadenylate synthase-like protein | 0.21 | 0.43 | **** |
| EPSTI1 | Epithelial-stromal interaction protein 1 | 0.39 | 0.42 | **** |
| MMP2 | Matrix metalloproteinase-2 | 3.23 | 0.39 | **** |
| UNC5B | Netrin receptor UNC5B | 0.20 | 0.38 | **** |
| PHLDA1 | Pleckstrin homology-like domain family A member 1 | 0.54 | 0.36 | **** |
| downregulated | ||||
| CDT1 | DNA replication factor | 3.34 | −0.57 | **** |
| KIF20A | Kinesin-like protein KIF20A | 3.54 | −0.53 | **** |
| ESPL1 | Separin | 1.27 | −0.53 | **** |
| SPC24 | Kinetochore protein Spc24 | 2.20 | −0.53 | **** |
| MYBL2 | Myb-related protein B | 2.33 | −0.52 | **** |
| KIF18B | Kinesin-like protein KIF18B | 1.66 | −0.51 | **** |
| FAM111B | Protein FAM111B | 0.68 | −0.51 | **** |
| TPX2 | Targeting protein for Xklp2 | 7.41 | −0.50 | **** |
| IQGAP3 | Ras GTPase-activating-like protein IQGAP3 | 1.59 | −0.50 | **** |
| PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | 1.88 | −0.50 | **** |
‡ RPKM (Reads Per Kilobase Million) of control MCs. **** p ≤ 0.0001.