Table 2.
Compositions of scaffolds fabricated from CaP nanoparticles *.
| Part I | |||||||||
| Calcium phosphate particles |
Solid Content in the slurry
(wt.%) |
Proportion
HA/β-TCP (%) |
Sintering
Temperature (°C) |
||||||
| HA | 20–40 | 100/0 | 800–1200 | ||||||
| CDHA ** | 20–40 | 0/100 | 800–1200 | ||||||
| HA/CDHA ** | 40 | 80/20 50/50 20/80 |
900–1200 | ||||||
| Part II | |||||||||
| Samples | Tests | ||||||||
|
Scaffolds
HA/β-TCP |
S.C
(wt.%) |
S.T
(°C) |
XRD | FESEM | MECHANICS | BIO-ACTIVITY | µCT/ LDH/ DNA | ||
| 100HA | 20 | 1100,1150,1200 | 1200 | ✓ | - | ✓ | 1150,1200 | ||
| 30 | 1100,1200 | - | ✓ | - | ✓ | 1200 | |||
| 40 | 1100,1150,1200 | 1200 | ✓ | 1150,1200 | ✓ | 1100,1200 | |||
| 80HA/20β−ΤCP | 20 | 1150, 1200 | - | ✓ | ✓ | - | - | ||
| 40 | 1150, 1200 | 1200 | ✓ | ✓ | - | - | |||
| 50HA/50β−ΤCP | 20 | 1150,1200 | - | ✓ | ✓ | - | - | ||
| 40 | 1150,1200 | 1200 | ✓ | ✓ | - | 1100,1200 | |||
| 20HA/80β−ΤCP | 2040 | 1150, 1200 1150, 1200 |
- 1200 |
✓ ✓ |
✓ ✓ |
- - |
- - |
||
| 100β-TCP | 2040 | 1150, 1200 1150, 1200 |
1200 1200 |
✓ ✓ |
✓ ✓ |
- - |
- - |
||
* HA, hydroxyapatite; CDHA, calcium deficient hydroxyapatite; S.C, solid content; S.T., sintering temperature; XRD, X-Ray diffraction; FESEM, field emission scanning electron microscopy; µCT, micro computed tomography; LDH, lactate dehydrogenase; ** CDHA with temperature transforms into β-TCP; ✓ all compositions tested.