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. 2019 Mar 31;20(7):1605. doi: 10.3390/ijms20071605

Figure 2.

Figure 2

Schematic model of putative HDAC6i effect in human neurons: HDAC6i increases K49-β-catenin acetylation, which results in membrane localization of β-catenin. β-catenin binds to N-cadherin and recruits PDZ-containing proteins involved in synaptic stabilization.