Table 2.
Gene expression of TRPA1 and TRPV1 in untreated and treated human IVD cells (2D). n = 5 donors. Values show fold change relative to the untreated cells. In case of expression under the detection limit, dCt was set at 40 cycles.
Treatment | Untreated | IL-1β 5 ng/mL | IL-1β 10 ng/mL | TNF-α 5 ng/mL | TNF-α 10 ng/mL |
---|---|---|---|---|---|
TRPA1 | No expression | 385.18 ± 233.06 | 333.42 ± 199.80 | 842.06 ± 659.98 | 780.23 ± 600.17 |
TRPV1 | Expression | 0.64 ± 0.18 | 0.69 ± 0.23 | 0.53 ± 0.11 | 0.45 ± 0.22 |