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. 2019 Mar 27;20(7):1538. doi: 10.3390/ijms20071538

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The levels of MDA, GSH and enzymatic activity of SOD and CAT were determined in the mid brain tissues of rats from different experimental groups. ROT treated rats showed significant (*** p < 0.01) increase in MDA (A) and decrease in GSH (B) levels when compared to control rats. Thymol treatment to ROT administered rats showed significantly (## p < 0.05) decreased level of MDA and increased (## p < 0.01) level of GSH. Moreover, ROT challenge also showed significant (* p < 0.05) decreased enzymatic activity of SOD (C) and CAT (D) when compared CONT rats. Thymol treatment to ROT challenged rats significantly (# p < 0.05) increased the activities of SOD and CAT when compared to ROT alone injected rats. The values are presented as mean ± SEM (n = 6–8).