Table 1.
Proteins with significantly up-regulated expression in CHIKV- and ZIKV-infected cells.
| Proteoform Name | Gene Name | Uniprot ID | Average log2 Ratio |
|---|---|---|---|
| Chikungunya virus infected cells proteins | |||
| Interferon-induced GTP-binding protein Mx1 | MX1 * | P20591 | 5.043 |
| Interferon-induced protein with tetratricopeptide repeats 3 | IFIT3 * | O14879 | 3.591 |
| Interferon-induced protein with tetratricopeptide repeats 1 | IFIT1 * | P09914 | 3.449 |
| Interferon-induced protein with tetratricopeptide repeats 2 | IFIT2 | P09913 | 2.954 |
| Ubiquitin-like protein ISG15 | ISG15 * | P05161 | 2.580 |
| Probable ATP-dependent RNA helicase DDX58 | DDX58 * | O95786 | 2.444 |
| Signal transducer and activator of transcription 1-alpha/beta | STAT1 * | P42224 | 1.659 |
| 2′-5′-oligoadenylate synthase 3 | OAS3 * | Q9Y6K5 | 1.626 |
| Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | SAMHD1 * | Q9Y3Z3 | 1.208 |
| HLA class I histocompatibility antigen, B-45 alpha chain | HLA-B | P30483 | 1.119 |
| Cytosol aminopeptidase | LAP3 | P28838 | 1.049 |
| Interferon-induced 35 kDa protein | IFI35 | P80217 | 1.015 |
| E3 ubiquitin-protein ligase RNF213 | RNF213 | Q63HN8 | 0.895 |
| Gamma-interferon-inducible protein 16 | IFI16 | Q16666 | 0.878 |
| Double-stranded RNA-activated protein kinase | EIF2AK2 * | P19525 | 0.838 |
| HLA class I histocompatibility antigen, A-69 alpha chain | HLA-A | P10316 | 0.752 |
| Zika virus infected cells proteins | |||
| Interferon-induced GTP-binding protein Mx1 | MX1 * | P20591 | 5.622 |
| Interferon-induced protein with tetratricopeptide repeats 1 | IFIT1 * | P09914 | 3.362 |
| Interferon-induced protein with tetratricopeptide repeats 3 | IFIT3 * | O14879 | 3.076 |
| Ubiquitin-like protein ISG15 | ISG15 * | P05161 | 2.430 |
| 2′-5′-oligoadenylate synthase 3 | OAS3 * | Q9Y6K5 | 2.190 |
| Poly [ADP-ribose] polymerase 9 | PARP9 | Q8IXQ6-2 | 2.118 |
| Phospholipid scramblase 1 | PLSCR1 | O15162 | 2.085 |
| Probable ATP-dependent RNA helicase DDX58 | DDX58 * | O95786 | 1.974 |
| Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | SAMHD1 * | Q9Y3Z3 | 1.739 |
| Signal transducer and activator of transcription 1-alpha/beta | STAT1 * | P42224 | 1.440 |
| Synaptopodin-2 | SYNPO2 | Q9UMS6 | 1.415 |
| E3 ubiquitin-protein ligase DTX3L | DTX3L | Q8TDB6 | 1.397 |
| 2′-5′-oligoadenylate synthase 1 | OAS1 | P00973 | 1.135 |
| E3 ubiquitin-protein ligase TRIM21 | TRIM21 | P19474 | 1.085 |
| Double-stranded RNA-activated protein kinase | EIF2AK2 * | P19525 | 1.071 |
| Interferon-induced GTP-binding protein Mx2 | MX2 | P20592 | 0.993 |
* Common proteins for CHIKV and ZIKV.