Effects of MitoQ and DecylTPP on mitochondrial bioenergetics. Plots of respiratory control experiments showing the time-dependent effects of MitoQ (open circles) and DecylTPP (open grey triangles) at (A) 1 µM, (B) 5 µM, and (C) 10 µM on oxygen consumption rate (OCR) changes at compared to control (open squares). A respiratory function ‘stress’ test was carried out using the sequential addition of oligomycin (Oligo, 1 μg/mL), FCCP (0.3 μM), and rotenone/antimycinA combined (Rot/AntiA, 1 μM) to detect respiratory parameters (ATP turnover capacity, proton leak and spare respiratory capacity).