. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: Bioorg Med Chem. 2019 Mar 8;27(9):1776–1788. doi: 10.1016/j.bmc.2019.03.019

Table 1.

MIC (μg/mL (fold reduction)) of colistin with in-house library adjuvants dosed at 60 μM.

	A. baumannii 4106	K. pneumoniae B9	A. baumannii ATCC 17978^+mcr−1	E. coli ATCC 25922 ^mcr−1
No compound	1024 μg/mL	1024 μg/mL	16 μg/mL	8 μg/mL
1 (19.3 μg/mL)	4 (256)	1 (1024)	0.5 (32)	1 (8)
2 (24.7 μg/mL)	2 (512)	0.5 (2048)	0.5 (32)	1 (8)
3 (19.9 μg/mL)	16 (64)	8 (128)	1 (16)	4 (2)
4 (20.8 μg/mL)	32 (32)	256 (4)	4 (4)	4 (2)
5 (16.1 μg/mL)	512 (2)	1024 (0)	16 (0)	8 (0)
6 (15.2 μg/mL)	512 (2)	1024 (0)	8 (2)	8 (0)