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. Author manuscript; available in PMC: 2019 Apr 24.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2019 Jan 28;54(1):1–10. doi: 10.1080/10409238.2018.1564730

Figure 3.

Figure 3.

The ZZ domain of ZZZ3 recognizes histone H3K4ac and modulates ATAC-dependent histone acetylation. (a) Superimposition of the mean position of acetylated and unmodified Lys4 in the ensembles of the structures of the ZZZ3 ZZ-H3K4ac and ZZ-H3K4 complexes (pdb 6E83 and 6E86). Each ensemble contains 20 NMR structures. (b) Schematic diagram of the human ATAC complex and the interpaly between writing of and binding to the indicated acetylated PTMs (see color version of this figure at www.tandfonline.com/ibmg).