Figure 2.

Immunophenotyping of tumour necrosis factor (TNF)-α-secreting alveolar macrophages (AMs). (A) Shown are the percentages of tumour necrosis factor-α-secreting AMs from patients with systemic sclerosis (SSc) without fibrosing alveolitis (FA), patients with FA and normal individuals (Norm) that were identified by the monoclonal antibodies (mAbs) RFD1, RFD7 and RFD9 (the data are presented as means ± SEM). (B) Shown are the average absolute percentages of AMs from each subject group identified by the mAbs RFD1, RFD7 and RFD9. The solid areas under each bar represent the percentage of each RFD-identified AM population that was secreting TNF-α.