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Transmission electron micrograph of non-treated (A–F) and 50 mg I-BET-151/kg/day treated (G–L) mouse right ventricle (A–C,G–I) and left ventricle (D–F,J–L). SM indicates sub-sarcolemmal mitochondria; IM, interfibrillar mitochondria; PM, perinuclear mitochondria, Vac, vacuole; N, nucleus; M, M line; Z, Z line. Asterisks indicate lipid droplets. Bar scale is indicated on each micrograph. Selection of the most representative pictures from three animals per group.
