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. 2019 Apr 1;20(7):1620. doi: 10.3390/ijms20071620

Figure 5.

Figure 5

STAT1, STAT2, MX and PKR protein expression of GFAP+ astrocytes, NogoA+ oligodendrocytes, and IBA1+ microglia/macrophages in cerebellar lesions of canine distemper virus-infected dogs. (AC) STAT1 is expressed by astrocytes, oligodendrocytes and microglia/macrophages. (DF) STAT2 was detected in oligodendrocytes and activated microglia/macrophages (gitter cells). (GI) MX was found in astrocytes, oligodendrocytes and microglia/macrophages. (JL) PKR is expressed by astrocytes and oligodendrocytes but not by microglia/macrophages. The majority of PKR+ cells in L are most likely lymphocytes. Immunofluorescence double-staining using bisbenzimide as nuclear counterstaining. Bars, 50 µm.