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. 2019 Apr 7;24(7):1363. doi: 10.3390/molecules24071363

Table 2.

The IC50 (μmol/L) of different single agents in HCC cell lines.

SK-Hep-1 SNU-423
Ponatinib (μmol/L) 0.288 ± 0.044 0.553 ± 0.041
Sunitinib (μmol/L) 0.568 ± 0.070 2.720 ± 0.036
Sorafenib (μmol/L) 3.896 ± 0.037 3.125 ± 0.034
Dasatinib (μmol/L) 0.902 ± 0.107 9.758 ± 0.044
Pazopanib(μmol/L) 3.951 ± 0.041 9.777 ± 0.030
Bosutinib (μmol/L) 0.840 ± 0.042 3.062 ± 0.041
Gefitinib (μmol/L) 5.557 ± 0.029 5.752 ± 0.048
Afatinib (μmol/L) 1.218 ± 0.031 2.400 ± 0.024
Midostaurin (μmol/L) 3.363 ± 0.053 1.640 ± 0.070

The IC50 values were determined from the data in Figure 1A. Individual IC50 results are the mean ± SD from at least three separate experiments.