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. 2019 Apr 3;20(7):1661. doi: 10.3390/ijms20071661

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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IMM-H004 decreases Permanent focal cerebral ischemia-induced brain inflammation in aged rats. (A) RT-PCR analysis for mRNA levels of CKLF1, CCR4, IL-1β, and TNF-α in hippocampus, cortex, and striatum of aged rats. (B) Representative blots and densitometry data for CKLF1, CCR4, IL-1β, and TNF-α hippocampus, cortex, and striatum of aged rats. Data are shown as the mean ± SD after normalization to the sham (n = 6/group). ### p < 0.001 vs. sham; ** p < 0.01 vs. model; *** p < 0.001 vs. model.