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. 2019 Apr 3;20(7):1661. doi: 10.3390/ijms20071661

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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CKLF1 is necessary for IMM-H004 to exert protective effects against brain ischemia. (A) Representative TTC staining images, and analysis of infarction area and edema ratio. (B) Statistical analysis of the Zea Longa test scores, forelimb slips, hanging test scores, and screen test scores in CKLF1^−/− rats. All the data are shown as the mean ± SD, a part of data are shown as the mean ± SD after normalization to the sham (n = 6/group). # p < 0.05 vs. sham; ## p < 0.01 vs. sham; ### p < 0.001 vs. sham.