Table 3.
Effect of dihydrochalcone (1) on glycosylated haemoglobin levels and AGEs in Kidney of diabetic mice.
Groups | Glycosylated Haemoglobin (%) | AGEs (RFU/mg Protein) |
---|---|---|
NormaL controL | 3.52 ± 0.7 a | 1.71 ± 0.9 a |
Diabetic controL | 9.45 ± 1.1 a | 3.8 ± 0.8 |
D + 1 (25 mg/dL) | 7.61 ± 1.8 | 3.0 ± 0.7 |
D + 1 (50 mg/dL) | 6.27 ± 0.9 a | 2.6 ± 0.9 |
D + 1 (100 mg/dL) | 4.3 ± 0.8 a | 2.0 ± 0.6 |
D + Met (200 mg/dL) | 4.9 ± 0.6 a | 1.9 ± 0.7 |
Results are expressed as mean ± SD of five mice in each group to five weeks of experimentation. Values a p < 0.05 vs. diabetic control (D).