Fig. 3.

Mirror induced behavior changes in mice. a A modified open field with mirrors on the four sides of the inner wall. b Representative traces showed the movement of the mice in the open field with (left) and without mirror (right) during 15–30 min after being placed in the open field. The red and blue rectangles represented the border of peripheral and center zones individually. c Mice in the open field with mirror spent more time in the central zone during 15–45 min after being placed in the open field compared with those put in the open field without mirror (*p < 0.05, **p < 0.01, n = 8 for each group, Student’s t-test). The time was displayed as a ratio of the time spent in the central zone with the time spent in the central zone during the first 15 min after being placed in the open field. d The travel distance had no significant variance between the open field with mirror and without mirror group