Table 4.
The effect of Ophiorrhiza rugosa extracts on intestinal transit in mice using a charcoal meal as a marker.
| Treatment (mg/kg) | Total Length of Intestine (cm) | Distance Travelled by Marker (cm) | Peristalsis Index (%) | % Inhibition Relative to Control |
|---|---|---|---|---|
| Control (0.1 mL/mouse) | 48.60 ± 0.51 | 41.40 ± 0.93 | 85.19 ± 1.74 | |
| Loperamide (5) | 49.20 ± 0.58 | 20.80 ± 0.73 | 42.26 ± 1.32 *** | 57.73 |
| EEOR (100) | 44.20 ± 0.37 ** | 29.20 ± 0.58 ** | 66.07 ± 1.32 *** | 33.92 |
| EEOR (200) | 43.00 ± 0.44 ** | 24.80 ± 0.86 *** | 57.69 ± 2.08 *** | 42.30 |
| EEOR (400) | 48.30 ± 0.25 *** | 20.10 ± 1.36 *** | 41.66 ± 3.02 *** | 58.33 |
Significantly different when compared with that of the control group at ** P < 0.01, *** P < 0.001. Results are presented as mean ± SEM (n = 6).