Table 5.
Anti-inflammatory activity of Ophiorrhiza rugosa extract on histamine-induced paw edema.
| Treatment (mg/kg) | Paw Volume (mm) (% Inhibition) | |||
|---|---|---|---|---|
| 1 h | 2 h | 3 h | 4 h | |
| Control (0.1mL/mouse) | 0.454 ± 0.010 | 0.392 ± 0.012 | 0.340 ± 0.007 | 0.312 ± 0.008 |
| Diclofenac-Na (10) | 0.350 ± 0.004 *** (42.42) |
0.290 ± 0.007 *** (60.29) |
0.264 ± 0.010 *** (66.66) |
0.248 ± 0.012 *** (78.57) |
| EEOR (100) | 0.422 ± 0.005 ** (11.11) |
0.358 ± 0.015 *** (17.64) |
0.310 ± 0.010 *** (23.8) |
0.290 ± 0.004 ** (21.42) |
| EEOR (200) | 0.398 ± 0.007 *** (20.20) |
0.334 ± 0.009 *** (30.88) |
0.294 ± 0.006 *** (35.71) |
0.278 ± 0.006 *** (32.14) |
| EEOR (400) | 0.344 ± 0.012 *** (38.38) |
0.300 ± 0.006 *** (42.64) |
0.260 ± 0.005 *** (54.76) |
0.246 ± 0.005 *** (57.14) |
Each value is expressed as mean ± SEM (n = 6). ** P < 0.01, *** P < 0.001 compared with the control group (Dunnett’s test).