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. 2019 Apr 24;19:336. doi: 10.1186/s12879-019-3968-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Chest CT (a-e) a) a mass and pleural effusion in the left lower lung on October 28, 2016. b) The mass in the left lower lobe was obviously smaller than that a) on November 2, 2016. c) The size of the nodule in the left lung tended to be stable with little change on April 26, 2017 (seven and a half months after taking apatinib). d) The nodule in the left lung progressed nine and a half months after taking apatinib. e) The lesions significantly improved on September 4, 2018. f) Bronchial stenosis with nodular projections. g) Yeast-like cell could be identified in the endobronchial nodule (PAS original magnification × 1000)