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. 2019 Apr 24;7:25. doi: 10.1186/s40560-019-0379-z

Table 2.

Proportion of days utilizing analgesia and sedation

2010 2016 Difference (95% CI) p value
Analgesia
 Overall 23,854/52803 (45%) 25,017/40612 (62%) 0.164 (0.160 to 0.168) < 0.001
 Europe 11,472/22005 (52%) 10,931/15592 (70%) 0.180 (0.173 to 0.187) < 0.001
 US/Canada 2142/4984 (43%) 1054/1993 (53%) 0.099 (0.083 to 0.115) < 0.001
 Asia 3033/9335 (32%) 4398/10096 (44%) 0.111 (0.103 to 0.119) < 0.001
 Africa 254/869 (29%) 499/912 (55%) 0.255 (0.224 to 0.286) < 0.001
 Australia/New Zealand 1579/3094 (51%) 533/672 (79%) 0.283 (0.259 to 0.307) < 0.001
 Latin America 5374/12516 (43%) 7602/11347 (67%) 0.241 (0.233 to 0.249) < 0.001
Sedation
 Overall 24,925/52803 (47%) 23,520/40612 (58%) 0.107 (0.102 to 0.112) < 0.001
 Europe 11,773/22005 (54%) 10,468/15592 (67%) 0.136 (0.129 to 0.143) < 0.001
 US/Canada 2439/4984 (49%) 1030/1993 (52%) 0.027 (0.008 to 0.046) 0.003
 Asia 3401/9335 (36%) 4507/10096 (45%) 0.082 (0.073 to 0.091) < 0.001
 Africa 281/869 (32%) 500/912 (55%) 0.225 (0.192 to 0.258) < 0.001
 Australia/New Zealand 2016/3094 (65%) 577/672 (86%) 0.207 (0.183 to 0.231) < 0.001
 Latin America 5015/12516 (40%) 6438/11347 (57%) 0.167 (0.158 to 0.176) < 0.001