Table 4.

Proportion of days utilizing spontaneous awakening trials

	2010	2016	Difference (95% CI)	p value
Overall	4848/24925 (20%)	4963/23520 (21%)	0.017 (0.013 to 0.021)	< 0.001
Europe	1771/11773 (15%)	1892/10468 (18%)	0.03 (0.023 to 0.037)	< 0.001
US/Canada	589/2439 (24%)	356/1030 (35%)	0.104 (0.082 to 0.126)	< 0.001
Asia	1017/3401 (30%)	1361/4507 (30%)	0.003 (− 0.006 to 0.012)	0.521
Africa	92/281 (33%)	77/500 (15%)	− 0.173 (− 0.198 to − 0.148)	< 0.001
Australia/New Zealand	446/2016 (22%)	120/577 (21%)	− 0.013 (− 0.042 to 0.016)	0.360
Latin America	933/5015 (19%)	1157/6438 (18%)	− 0.006 (− 0.015 to 0.003)	0.165

Proportion of days with SAT performed out of the total days when any sedation was received