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. 2019 Apr 24;12:40. doi: 10.1186/s13045-019-0728-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — CD73⁻ CD8⁺ T cells from AML patients showed phenotypic and transcriptional defects that a consistent with exhaustion. a HLA-DR expression on CD73⁻ and CD73⁺ CD8 T cells from AML patients (n = 19). P values were obtained by Wilcoxon matched-pairs signed rank test. b Correlative analysis of CD73 and HLA-DR is shown. Pearson’s test was used to test for correlations. c Intracellular expression of EOMES on CD73⁻ and CD73⁺ CD8⁺ T cells from AML patients (n = 13). P values were obtained by paired t test