Fig. 2.

lncRNA CCAT1 was overexpressed in 5-FU resistant colon cancer cells. a. CCK-8 essay was performed to examine the IC50 value for HCT 116, HT-29, HCT 116/5-FU and HT-29/5-FU cells after 5-FU treatment. b. The expression of CCAT1 in HCT 116/5-FU, HT-29/5-FU cell lines were determined by qRT-PCR. c. Flow cytometry analysis was used to detected the apoptosis rate of HCT 116, HT-29, HCT 116/5-FU and HT-29/5-FU cells after 5-FU treatment. Error bars represent the mean ± SD. ^**P < 0.01 compared with the HCT 116 or HT-29 group