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. 2019 Apr 23;20:9. doi: 10.1186/s12860-019-0188-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Role of CCAT1 in chemosensitivity of parental or 5-FU-resistant colon cancer cell lines. a, b. qRT-PCR assay was performed to examine the expression of CCAT1 after the transfection of HCT 116 or HT-29 cells with pcDNA3.1-CCAT1 and of HCT 116/5-FU or HT-29/5-FU cells with siRNA-CCAT1. c, d. IC50 values for 5-FU in HCT 116 or HT-29 cells transfected with pcDNA3.1-CCAT1 and HCT 116/5-FU or HT-29/5-FU cells transfected with siRNA-CCAT1. ^**P < 0.01 compared with respective NC group