Figure 6.

Effects of paeoniflorin (PF) on endothelial injury, inflammatory factors, and oxidative stress levels in rats fed with different diets for 4 weeks. Rats in the SHG and IHG groups were fed with low and high glycemic diet, respectively. von Willebrand factor (VWF) (a), sE-selectin (b), TNF-α (c), PECAM-1 (d), AOPPs (e), and T-AOC (f) levels were determined in the various groups. Data are presented as mean ± standard deviation. ^∗P < 0.05 and ^∗∗P < 0.01 compared with the control rats. Cont: control; SHG: stable high blood glucose; IHG: intermittent high blood glucose; MH: metformin hydrochloride.