Table 2.
Overall survival | Disease-specific survival | Disease-free survival | |||||||
---|---|---|---|---|---|---|---|---|---|
Multivariate Model† | Multivariate Model† | Multivariate Model† | |||||||
| |||||||||
Variable | HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P |
| |||||||||
Age (year) | <0.001 | 0.008 | 0.005 | ||||||
>65 | Ref | Ref | Ref | ||||||
≤65 | 2.05 | 1.36-3.08 | <0.001 | 1.86 | 1.18-2.93 | 0.008 | 1.77 | 1.20-2.64 | 0.005 |
Size (cm) | 0.012 | 0.005 | 0.006 | ||||||
≤2 | Ref | Ref | Ref | ||||||
2-5 | 1.05 | 0.50-2.18 | 0.905 | 1.03 | 0.43-2.51 | 0.943 | 1.22 | 0.58-2.57 | 0.603 |
>5 | 1.87 | 1.20-2.93 | 0.006 | 2.17 | 0.95-4.93 | 0.065 | 1.96 | 1.28-3.01 | 0.002 |
T-stage | <0.001 | <0.001 | <0.001 | ||||||
T1 | Ref | Ref | Ref | ||||||
T2 | 2.19 | 0.67-7.16 | 0.195 | 3.08 | 0.64-14.85 | 0.161 | 2.54 | 0.78-8.28 | 0.122 |
T3 | 3.40 | 1.11-10.49 | 0.033 | 4.36 | 0.95-19.93 | 0.058 | 4.44 | 1.45-13.62 | 0.009 |
T4a | 5.21 | 1.76-15.47 | <0.001 | 7.40 | 1.68-32.58 | 0.008 | 6.19 | 2.07-18.48 | 0.001 |
T4b | 9.36 | 2.98-29.44 | <0.001 | 16.00 | 3.46-74.02 | <0.001 | 12.87 | 4.05-40.94 | <0.001 |
N-stage | <0.001 | <0.001 | 0.001 | ||||||
N0 | Ref | Ref | Ref | ||||||
N1 | 1.42 | 0.78-2.60 | 0.258 | 1.39 | 0.71-2.71 | 0.337 | 1.32 | 0.74-2.34 | 0.349 |
N2 | 3.49 | 1.86-6.53 | <0.001 | 3.49 | 1.80-6.80 | <0.001 | 2.43 | 1.34-4.42 | 0.004 |
N3a | 3.59 | 1.96-6.56 | <0.001 | 3.70 | 1.88-7.27 | <0.001 | 2.81 | 1.58-5.01 | <0.001 |
N3b | 6.72 | 2.31-19.57 | <0.001 | 6.06 | 1.85-19.87 | 0.003 | 3.18 | 1.13-9.00 | 0.029 |
†Adjusted for age, sex, BMI, family history of gastric cancer, interval between gastrectomy and remnant gastric cancer, previous disease, previous operation type, reconstruction, comorbidity, complication, ASA score, tumor location, lymphovascular invasion, approach, combined resection, histology, macroscopic type, retrieved lymph node, complication, and adjuvant chemotherapy.