Table 1.
USP7 substrates
| Substrate name | Reference | Substrate name | Reference |
|---|---|---|---|
| Transcription factors | Epigenetic control of gene expression | ||
| p53 | (18) | RING1B | (39) |
| HDM2 | (19) | Bmi1 | (40) |
| Rb | (105) | Histone H2B | (106) |
| FOX(O)3 | (46) | DNMT1 | (107) |
| FOX(O)4 | (46) | UHRF1 | (37) |
| PTEN | (12) | RNF168 | (23) |
| β-catenin | (71) | MLL5 | (43) |
| PPARγ | (108) | Tip60 | (42) |
| N-Myc | (109) | UbE2E1 | (75) |
| DNA replication/Cell cycle control | PHF8 | (14) | |
| CHFR | (110) | Telomere proteins | |
| Bub3 | (111) | TPP1 | (112) |
| SUMO | (34) | Immune response | |
| DNA damage response/DNA repair | NFºB | (113) | |
| DAXX | (114) | TRAF6 | (115) |
| Polymerase η | (32) | IKKγ | (115) |
| HLTF | (29) | TRIM27 | (116) |
| Rad 18 | (30) | Viral proteins | |
| Clapsin | (27) | EBNA1 from EBV | (117) |
| Chk1 | (26) | ICP0 from HSV-1 | (49) |
| UVSSA | (28) | vIRF1 from KSHV | (54) |
| Mule/ARF-BP1 | (118) | vIRF4 from KSHV | (53) |
| XPC | (22) | LANA from KSHV | (51) |
| Epigenetic control of gene expression | UL35 from HCMV | (55) | |
| MEL18 | (40) | E1B from Adenovirus | (56) |