Table 1. The effects of desipramine on metabolic indices.
| Index | NC group | DC group | DTD group |
|---|---|---|---|
| FBS (mmol/l) | 8.44 ± 2.48 | 30.98 ± 5.63* | 25.32 ± 2.84*# |
| TG (mmol/l) | 0.80 ± 0.16 | 0.94 ± 0.57 | 0.81 ± 0.32 |
| TC (mmol/l) | 1.44 ± 0.36 | 3.47 ± 1.08* | 2.87 ± 0.36* |
| HOMA-IR | 2.02 ± 0.69 | 18.65 ± 6.37* | 11.15 ± 3.84*# |
| Insulin (μIU/l) | 7.86 ± 2.02 | 23.49 ± 4.78* | 18.94 ± 4.32*# |
All indices were determined after desipramine treatment for 12 weeks in NC group (n=6), DC group (n=6), and MTD group (n=6).
Abbreviations, FBS, fasting blood sugar; HOMA-IR, homeostasis model assessment-estimated insulin resistance; TC, total cholesterol; TG, triglyceride. Values are means ± S.D. *P<0.05, contrasted to normal control group. #P<0.05, contrasted to diabetic control group.