Table 9.
Cytotoxicity assays.
SLS (POSITIVE CONTROL)* | ||||||
---|---|---|---|---|---|---|
Dosage (mg/mL) | 0.5 | 0.25 | 0.13 | 0.06 | 0.03 | |
% cell vitality | 1.9 | 1.1 | 12.6 | 1,112.9 | 106.7 | |
Standard deviation | 0.3 | 0.3 | 5.6 | 0.3 | 2.6 | |
VAGINAL CAPSULES WITH BPL005 ADDED** | ||||||
Dosage (mg/mL) | 5 | 0.25 | 1.25 | 0.63 | 0.31 | 0.16 |
% cell vitality | 88 | 78.9 | 76.4 | 82.9 | 78.9 | 76.2 |
Standard deviation | 1.1 | 0.5 | 0.2 | 2.5 | 1.5 | 1.3 |
IC50 = 0.10 mg/mL. Cell mortality was >30% in the first 3 dilutions tested.
IC50 ≥ 5 mg/mL. Cell mortality was <30% in all the dilutions tested.